Clinical Risk Factors, DNA Variants, and the Development of Type 2 ...

Posted on Tue, 02 Dec 2008 08:36:39 -0800 in American diabetes assoc

New research suggests that common genetic variants associated with type 2 diabetes were a little more effective in predicting future development of the disease than risk factors alone. The tea...

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Clinical Risk Factors, DNA Variants, and the Development of Type 2...

Posted on Mon, 01 Dec 2008 12:28:39 -0800 in Major risk factors for type 2 diabetes

New research suggests that common genetic variants associated with 2 diabetes were a litt...

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Comprehensive Association Study of Type 2 Diabetes and Related ...

Posted on Sun, 02 Nov 2008 16:03:38 -0800 in Jackson diabetes

OBJECTIVE—Type 2 diabetes is a common complex disorder with environmental and genetic components. We used a candidate gene–based approach to identify single nucleotide polymorphism (SNP) va...

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Comprehensive Association Study of Type 2 Diabetes and Related ...

Posted on Thu, 30 Oct 2008 08:04:39 -0700 in Diabetes control 2

We used a candidate gene–based approach to identify single nucleotide polymorphism (SNP) variants in 222 candidate genes that influence susceptibility to type 2 diabetes. RESEARCH DESIGN AND ...

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Two Single Nucleotide Polymorphisms Identify the Highest-Risk ...

Posted on Thu, 30 Oct 2008 04:02:39 -0700 in Diabetes screening tests

Overall, the sensitivity and specificity for the test were 98.57 and 99.67%, respectively. CONCLUSIONS—A two-SNP screening test can identify the highest risk heterozygous genotype for ...

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Comprehensive Association Study of Type 2 Diabetes and Related ...

Posted on Thu, 30 Oct 2008 04:01:40 -0700 in What is type 2 diabetes

OBJECTIVE—Type 2 diabetes is a common complex disorder with environmental and genetic components. We used a candidate gene–based approach to identify single nucleotide polymorphism (SNP) va...

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The IFIH1 Polymorphisms Are Significantly Associated with Type 1 ...

Posted on Fri, 17 Oct 2008 08:01:40 -0700 in Type 3 diabetes

Genome-wide association (GWA) studies revealed a number of single nucleotide polymorphisms (SNPs) significantly associated with type 1 diabetes (T1D). In an attempt to confirm some of th...

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Genome-Wide Linkage and Admixture Mapping of Type 2 Diabetes in ...

Posted on Sat, 11 Oct 2008 16:01:39 -0700 in Diabetes journal

We used a single nucleotide polymorphism map in a large cohort of 580 African American families to identify regions linked to type 2 diabetes (T2D), T2D age of diagnosis (AOD), and body mass in...

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Genome-Wide Linkage and Admixture Mapping of Type 2 Diabetes in ...

Posted on Fri, 10 Oct 2008 20:03:38 -0700 in Diabetes journal

We used a single nucleotide polymorphism map in a large cohort of 580 African American families to identify regions linked to type 2 diabetes (T2D), T2D age of diagnosis (AOD), and body mass in...

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Genome-Wide Linkage and Admixture Mapping of Type 2 Diabetes in ...

Posted on Fri, 10 Oct 2008 04:02:39 -0700 in Diabetes journal

We used a single nucleotide polymorphism map in a large cohort of 580 African American families to identify regions linked to type 2 diabetes (T2D), T2D age of diagnosis (AOD), and body mass in...

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Common Variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX ...

Posted on Mon, 29 Sep 2008 12:33:10 -0700 in Diabetes fasting

RESEARCH DESIGN AND METHODS— We genotyped 17 single nucleotide polymorhisms (SNPs) in 3210 unrelated Chinese Hans, including 424 participants with type 2 diabetes, 878 with impaired fasting...

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FTO Variants Are Associated With Obesity in the Chinese and Malay ...

Posted on Sun, 28 Sep 2008 12:01:30 -0700 in Diabetes associations

RESEARCH DESIGN AND METHODS— We examined associations between nine previously reported FTO single nucleotide polymorphisms (SNPs) with obesity, type 2 diabetes, and related traits in 4...

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A Common Nonsynonymous Single Nucleotide Polymorphism in the ...

Posted on Sat, 27 Sep 2008 00:03:38 -0700 in Type 1 diabetes

The type 2 nonsynonymous single nucleotide polymorphism (SNP) affecting aa325 lies with...

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Common Variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX ...

Posted on Fri, 26 Sep 2008 20:01:39 -0700 in Diabetes fasting

RESEARCH DESIGN AND METHODS— We genotyped 17 single nucleotide polymorhisms (SNPs) in 3210 unrelated Chinese Hans, including 424 participants with type 2 diabetes, 878 with impaired ...

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High-Density Single Nucleotide Polymorphism Genome-Wide Linkage ...

Posted on Sun, 07 Sep 2008 20:02:39 -0700 in Diabetes journal

RESEARCH DESIGN AND METHODS— To efficiently search for genomic regions harboring diabetic nephropathy genes, we conducted a scan using 5382 informative single nucleotide polymorphisms on 100 sibpai...

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Common variants in the adiponectin gene (ADIPOQ) associated with ...

Posted on Sun, 07 Sep 2008 20:01:41 -0700 in Diabetes journal

Variants in ADIPOQ have been inconsistently associated with adiponectin levels or diabetes. Using comprehensive linkage disequilibrium (LD) mapping, we genotyped single nucleotide polymorphisms...

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Common variants in the adiponectin gene (ADIPOQ) associated with ...

Posted on Sun, 07 Sep 2008 04:01:43 -0700 in Articles on diabetes

Variants in ADIPOQ have been inconsistently associated with adiponectin levels or diabetes. Using comprehensive linkage disequilibrium (LD) mapping, we genotyped single nucleotide polymorphisms...

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High-Density Single Nucleotide Polymorphism Genome-Wide Linkage ...

Posted on Fri, 05 Sep 2008 12:02:39 -0700 in Diabetes journal

RESEARCH DESIGN AND METHODS— To efficiently search for genomic regions harboring diabetic nephropathy genes, we conducted a scan using 5382 informative single nucleotide polymorphisms on 100 sibpai...

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2 diabetes gene position spot was confirmed again

Posted on Wed, 20 Aug 2008 00:01:39 -0700 in How is stress and diabetes related

... crowd’s research to 217 2 diabetes pedigree’s 713 members and 173, discovered that UrotensinII (tail compression element) in the gene a single nucleotide polymorphism position se...

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Two Single Nucleotide Polymorphisms Identify Highest-Risk Diabetes...

Posted on Tue, 19 Aug 2008 04:01:04 -0700 in Diabetes screening tests

Overall, the sensitivity for the test was 98.57% and was 99.67% specific. CONCLUSIONS:. A two SNP screening test can identify the highest risk heterozygous genotype for type 1 diabetes...

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